白病受尿路感染的影响:生化定量方法与自动尿液化学分析仪UC-3500之间的比较
Yi-Ju Chou1, Chun-Chun Yang2, Shang-Jen Chang3
1Division of Urology, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei 23142, Taiwan.
Diagnostics (Basel, Switzerland)
|November 14, 2023
概括
泌尿道感染 (UTI) 可能会影响尿检测的自动化尿液试剂条试验的准确性. 在使用这些测试进行可靠的白尿查之前,治疗尿路感染至关重要.
科学领域:
- 临床化学 临床化学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 诊断的准确性 诊断的准确性
背景情况:
- 自动化尿液试剂条试验是检测白尿的成本效益较高的方法.
- 尿路感染 (UTI) 对这些测试的准确性的影响尚未得到充分证实.
研究的目的:
- 通过生化和自动化试验条方法评估尿路感染对白蛋白尿症诊断的影响.
- 为了比较全自动尿液化学分析仪 (UC-3500) 在治疗尿路感染期间和之后诊断白蛋白尿的准确性.
主要方法:
- 预期从成年女性尿路感染患者收集尿液样本,在治疗塞法列克辛之前和之后.
- 通过生物化学定量方法和UC-3500进行尿液培养,例行尿液分析和白蛋白尿症诊断.
- 专性尿症定义为尿中的专蛋白与肌素比率 (UACR) ≥30 mg/g.
主要成果:
- 在54名患者中,44.44%的患者在尿路感染期间患有过渡性白色素尿.
- 在治疗后,定量UACR显著下降 (中位数为53 mg/g至9 mg/g).
- UC-3500在尿路感染期间 (42%) 与治疗后 (19%) 的假阳性率较高,与定量方法相对适度或良好.
结论:
- 泌尿道感染影响了专用尿试剂带测试对白色素尿的准确性.
- 尿路感染可能会导致过渡性白膜尿症或测试条带的错误阳性结果.
- 建议在使用自动化测试对白尿查之前排除或治疗尿路感染.
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