瘤标志物测试在临床实践中是否被适当地应用? 一个医疗保健声称数据分析数据分析
Sabrina M Stollberg1, Markus Näpflin1, Michael Nagler2
1Department of Health Sciences, Helsana Insurance Group, 8081 Zurich, Switzerland.
Diagnostics (Basel, Switzerland)
|November 14, 2023
概括
对查进行不适当的瘤标志物 (TM) 测试存在风险. 这项研究发现,只有41.6%的TM测试是合适的,突出了误解对患者的潜在危害,特别是在初级保健中.
科学领域:
- 在瘤学瘤学.
- 临床化学 临床化学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 瘤标志物 (TM) 对于癌症治疗监测至关重要.
- 不适当的TM测试,特别是查,带有错误结果,患者焦虑和不必要的程序的风险.
研究的目的:
- 评估瘤标志物测试在瑞士门诊机构的适当性.
- 确定与适当的TM测试请求相关的因素.
主要方法:
- 使用医疗保健索赔数据 (2018-2021) 的回顾性队列研究.
- 分析了7个常见的TM测试 (CEA,CA19-9,CA125,CA15-3,CA72-4,素,NSE) 的51,395个确定结果.
- 通过相关的癌症诊断或干预来定义适当性;使用多变量分析.
主要成果:
- 只有41.6%的TM决定是适当的.
- 一般医生占申请人数的44.3%,但适度率最低 (27.8%).
- 医疗瘤学家的要求是适当的TM测试的强有力的预测因素.
结论:
- 在门诊实践中,大量的TM检测是不合适的,特别是在初级保健中.
- 不适当的TM使用可能会导致患者由于误解结果而受到伤害.
- 优化TM检测协议对于减轻风险和改善患者的治疗结果至关重要.
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