肝细胞癌:监测,诊断,评估和管理
Jessica Elderkin1, Najeeb Al Hallak2, Asfar S Azmi2
1Wayne State University School of Medicine, Detroit, MI 48201, USA.
Cancers
|November 14, 2023
概括
通过监测对肝细胞癌 (HCC) 的早期检测至关重要. 患者外展和提供者提醒等干预措施可以提高HCC监测率,从而带来更好的结果.
科学领域:
- 肝病学和瘤学 肝病学和瘤学
- 癌症监测和早期发现
- 医疗干预和治疗方法
背景情况:
- 肝细胞癌 (HCC) 是全球癌症死亡的主要原因.
- 目前监测计划的不足利用需要为患者和提供者进行干预.
- 通过半年监测进行早期检测,可以改善高风险个体 (肝硬化,乙型肝炎) 的结果.
研究的目的:
- 为了强调肝细胞癌 (HCC) 监测的重要性.
- 讨论改善患者和提供者遵守监测协议的策略.
- 审查目前对HCC的诊断和管理方法.
主要方法:
- 关于HCC监测,诊断和治疗的当前文献的审查.
- 分析患者层面的干预措施 (邮件宣传,导航) 和提供者层面的干预措施 (EMR提醒,合规报告).
- 基于疾病阶段的诊断标准 (LI-RADS) 和治疗方式的讨论.
主要成果:
- 患者外展和导航增加了监控跟进.
- 针对供应商的干预措施提高了对HCC监测的认识和遵守.
- 先进的全身疗法,包括阿特佐利祖马布加贝瓦齐祖马布,在先进的HCC中显示出更好的生存率.
结论:
- 改善HCC监测需要多方面的患者和提供者层面的干预.
- 标准化报告 (LI-RADS) 和多学科评估是HCC管理的关键.
- 虽然仍然存在挑战,但系统疗法的进步和潜在的新辅助疗法为HCC患者提供了未来的希望.
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