相关实验视频

Updated: Jul 11, 2025

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Dynamic Imaging of Chimeric Antigen Receptor T Cells with [18F]Tetrafluoroborate Positron Emission Tomography/Computed Tomography

Published on: February 17, 2022

整合[18F]-氧葡萄糖正子发射断层扫描与计算机断层扫描,放射治疗和免疫调节,用于固体瘤的精密治疗

Conor M Prendergast¹, Egesta Lopci², Romain-David Seban^3,4

¹Department of Radiology, NewYork-Presbyterian, Columbia University Irving Medical Center, New York, NY 10032, USA.

|November 14, 2023

概括

[18F]-FDG PET/CT成像技术有助于评估结合放射治疗 (RT) 和免疫瘤学 (IO) 治疗癌症的方法. 它监测治疗反应,包括腹膜效应,并指导固体瘤的精密治疗.

科学领域:

在瘤学瘤学.
放射学放射学是一门学科.
免疫学免疫学免疫学

背景情况:

[18F]-FDG PET/CT对于癌症治疗质量至关重要.
将放射治疗 (RT) 与免疫瘤学 (IO) 药物的结合显示出有希望的结果.
了解局部和遥远部位的治疗反应,包括腹腔效应,是关键.

研究的目的:

探索PET/CT在RT/IO联合治疗固体瘤中的附加值.
为提供有关RT/IO管理时间表和响应监测的见解.
为了补充最近关于精确癌症治疗的联合指南.

主要方法:

使用[18F]-FDG PET/CT进行治疗反应评估.
评估RT和远部瘤部位的反应.
监测abscopal效应,超级进展,寡头进展,伪进展和与免疫相关的不良事件.

主要成果:

PET/CT增强了对RT/IO协同效应的评估.
它有助于建立最佳的RT/IO管理时间表.
PET/CT识别出新的反应模式和不良事件.

结论:

在结合RT和IO的精密疗法中,PET/CT提供了增量价值.
它为管理固体瘤提供了关键的见解.
这种成像模式有助于提高瘤医疗护理质量.

关键词:

在PET成像中使用PET成像.聚乙烯/聚乙烯/聚乙烯这是一种abscopal效应.免疫疗法免疫疗法辐射治疗疗法辐射治疗疗法这些是瘤生物标志物.瘤的超级进展.瘤转移的发生.

更多相关视频

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction

Published on: January 29, 2019

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells

Published on: February 8, 2018

相关概念视频

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET

Tumor Immunotherapy

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.