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肝细胞癌流行病学的变化在卡林西亚,奥地利,2012-2023年

Florian Hucke¹, Heleen Emmer¹, Roberto Emmer¹

¹Department of Internal Medicine and Gastroenterology (IMuG), Hepatology, Endocrinology, Rheumatology and Nephrology Including Emergency Medicine (ZAE), Klinikum Klagenfurt am Wörthersee, 9020 Klagenfurt, Austria.

|November 14, 2023

概括

肝细胞癌 (HCC) 发病率正在上升,年轻患者的诊断越来越多,非酒精性脂肪肝炎 (NASH) 病例增加. 在没有肝硬化的患者中,早期检测至关重要.

科学领域:

肝病学肝病学是一种肝病学.
在瘤学瘤学.
流行病学流行病学

背景情况:

肝细胞癌 (HCC) 是一个重大的全球健康挑战,其发病率正在上升.
尽管取得了进展,但HCC仍然是全球癌症相关死亡的主要原因.

研究的目的:

分析2012-2023年间Klinikum Klagenfurt am Wörthersee医院HCC病因和生存率的流行病学转变.
为了比较两个不同的时间间隔 (2012-2017年和2018-2023年) 的HCC患者人口统计和结果.

主要方法:

追溯性,单中心队列研究设计.
使用IBM SPSS.使用患者数据的统计分析.
两个五年期的比较,以确定趋势.

主要成果:

在后期 (2018-2023) 增加了HCC诊断,患者的平均年龄较小.
酒精仍然是主要病因,但非酒精性脂肪肝炎 (NASH) 病例显示出显著的上升趋势.
生存结果保持一致,尽管晚期HCC的增加和诊断的肝硬化患者数量越来越多,但肝硬化通常与NASH有关.

结论:

肝硬化症是一个持续的公共卫生问题,在没有先前存在肝硬化的人群中病例显著增加,通常与NAFLD/NASH有关.
预防策略和查必须适应HCC不断变化的流行病学,强调在非肝硬化人群中检测.
针对性的查和预防工作对于应对HCC日益增长的负担至关重要,特别是在与生活方式相关的疾病的背景下.

关键词:

奥地利奥地利奥地利奥地利奥地利纳什·纳什 (Nash Nash) 是一个名为纳什的城市.流行病学流行病学肝细胞癌是肝细胞癌.幸存率 HCC 的生存率

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