基于拉曼的技术在诊断任务的医疗应用中:一篇评论
Yulia Khristoforova1, Lyudmila Bratchenko1, Ivan Bratchenko1
1Department of Laser and Biotechnical Systems, Samara National Research University, 34 Moskovskoye Shosse, Samara 443086, Russia.
International journal of molecular sciences
|November 14, 2023
概括
拉曼光谱通过分析分子结构提供了一种非侵入性方法来诊断疾病. 本次审查强调了其在检测癌症,心血管和神经退行性疾病的生物标志物的潜力,尽管目前的局限性.
科学领域:
- 生物医学光学 生物医学光学
- 分析化学 分析化学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 拉曼光谱为非侵入性分析提供了高化学特异性.
- 它在医学诊断中的应用正在迅速发展.
- 准确的分子结构和成分分析对于疾病鉴定至关重要.
研究的目的:
- 审查医学诊断的基于拉曼的技术.
- 探索用于识别各种疾病的生物标志物的应用.
- 分析临床翻译目前的局限性和挑战.
主要方法:
- 关于传统拉曼光谱和表面增强拉曼光谱 (SERS) 的最新研究的综述.
- 专注于用于检测心血管疾病,癌症,神经退行性疾病和COVID-19的生物标志物的应用程序.
- 对已识别的基于拉曼的方法的诊断潜力和局限性的分析.
主要成果:
- 发现了几种基于拉曼的有前途的疾病识别应用.
- 对于受影响的个体,可以检测出显著的光谱特征.
- 这些方法的诊断能力各不相同,但已确定了具体的有前途的应用.
结论:
- 拉曼光谱和SERS显示出迅速检测疾病生物标志物的巨大潜力.
- 需要进一步的研究来克服局限性并使临床翻译成为可能.
- 基于拉曼的技术为非侵入性医学诊断提供了一个有希望的途径.
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