在胃肠道传染病中准肠道微生物群的治疗方法
Ziying Han1, Yiyang Min2, Ke Pang2
1Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Dongcheng District, Beijing 100730, China.
International journal of molecular sciences
|November 14, 2023
概括
肠道微生物组显著影响胃肠道感染. 本综述探讨了它在各种感染中的作用和潜在的治疗应用,包括便微生物群移植 (FMT).
科学领域:
- 胃肠道学和微生物学
- 肠道微生物组研究研究
- 传染性疾病 传染性疾病
背景情况:
- 越来越多的证据将肠道微生物组与胃肠道传染病联系起来.
- 像便微生物群移植 (FMT) 和益生菌等治疗方法越来越多地用于治疗腹等疾病.
- 肠道微生物在各种胃肠道感染中的确切作用以及肠道调制疗法的普遍有效性仍然不清楚.
研究的目的:
- 综合审查肠道微生物组在各种胃肠道传染病中的参与.
- 探索这些感染中的肠道微生物组的致病机制和治疗潜力.
- 通过微生物组调制,提供有关胃肠道感染的预防,诊断,预测和治疗的见解.
主要方法:
- 对最近的发展进行了全面的文献综述.
- 对肠道微生物组在特定感染中的作用的分析: * 杆菌, * 杆菌, * 霍乱病毒, * 肠道病毒, * 肠道病毒, * 沙门氏菌, * 血清型 Typhimurium, * 假菌, * 黄金菌, * 虫, * 虫, * 和 * 十二指甲虫*.
- 在胃肠道感染中包括有关真菌和工程细菌的信息.
主要成果:
- 肠道微生物组在一系列胃肠道传染病中发挥着重要而复杂的作用.
- 特定的微生物组成与不同的病原体和疾病状态有关.
- 新出现的数据表明,针对微生物组的向疗法的潜力很大,尽管普遍的疗效尚未确立.
结论:
- 肠道微生物组是胃肠道感染的关键因素,影响病原和疾病结果.
- 对微生物组与宿主相互作用的进一步研究对于制定有针对性的预防和治疗策略至关重要.
- 肠道调节疗法具有前景,但需要对特定的传染病原体和患者群体进行进一步的研究.
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