相关实验视频
Updated: Jul 11, 2025

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis
Published on: July 28, 2023
肠 - 肝 - 脑轴:从头到脚
Mauro Giuffrè1,2, Rita Moretti2
1Department of Internal Medicine (Digestive Diseases), Yale School of Medicine, Yale University, New Haven, CT 06510, USA.
肠-肝-脑轴连接肠道,肝脏和大脑. 这种复杂的网络影响着整体健康和疾病,强调了解这些相互作用的重要性.
科学领域:
- 神经科学是一个神经科学.
- 胃肠病学 胃肠病学
- 肝病学 肝病学是一种肝病学.
背景情况:
- 肠-肝-脑轴是一个复杂的通信网络.
- 它涉及肠道,肝脏和中枢神经系统.
- 这个轴的调节失调与各种疾病有关.
研究的目的:
- 为了阐明肠-肝-大脑轴内的复杂连接.
- 探索这些器官之间的通信机制.
- 了解这个轴在健康和疾病中的作用.
主要方法:
- 关于肠-肝-脑轴的现有文献的综述.
- 对参与器官间通信的信号通路的分析.
- 整合了来自神经科学,胃肠病学和肝病学的数据.
主要成果:
- 双向通信通道的详细地图.
- 确定关键的分子媒介和信号级联.
- 证据支持轴在代谢和神经系统疾病中的作用.
结论:
- 肠 - 肝 - 脑轴对于维持平衡至关重要.
- 了解这一轴为相关疾病提供了治疗目标.
- 需要进一步的研究才能完全解开它的复杂性.
更多相关视频
07:29Real-time Analysis of Gut-brain Neural Communication: Cortex wide Calcium Dynamics in Response to Intestinal Glucose Stimulation
Published on: December 29, 2023
10:05Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
相关概念视频
Spinal Nerves: Plexus II
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
Hepatic Portal System
At its core, the hepatic portal vein is the result of a confluence of the superior and inferior mesenteric veins along with the splenic vein. Each of these veins has a unique role. The superior mesenteric vein is...
Physiology of Enteric Nervous System and Gut Health
Sympathetic Pathways: Collateral Ganglia and Adrenal Medulla
Collateral Ganglia
Sympathetic preganglionic axons reach the collateral ganglia along the route of splanchnic nerves. These nerves bypass the sympathetic trunk and communicate with sympathetic postganglionic neurons housed in the prevertebral ganglia. These ganglia supply the organs of the abdominopelvic cavity.
The greater splanchnic nerve, formed by the...
Veins of the Abdomen and Pelvis
The inferior vena cava is fed by numerous smaller veins. The lumbar veins, for instance, drain the posterior abdominal wall, emptying both directly into the inferior vena cava and into the...
Anatomy of the Gastrointestinal System
Here's a detailed walkthrough of this complex system: