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基因组探索不同的分子表型,指导患者衍生的质母细胞细胞中泰莫佐洛米德抗药的发展

Federica Fabro1, Trisha V Kers1, Kate J Feller2

  • 1Department of Neurosurgery Rotterdam, Brain Tumor Center, Erasmus Medical Center Cancer Institute, Erasmus Medical Center, Wytemaweg 80, Ee2236, 3015 CN Rotterdam, The Netherlands.

International journal of molecular sciences
|November 14, 2023
PubMed
概括

质母细胞细胞通过适应性或非适应性途径对temozolomide产生耐药性. 了解这些独特的细胞行为对于改善质母细胞瘤治疗结果至关重要.

关键词:
质母细胞瘤 (glioblastoma) 是一种一个单细胞RNA测序.泰莫索洛米德的耐药性瘤异质性的异质性

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