银,其盐及其在医学和药房中的应用
Dominik Żyro1, Joanna Sikora1, Małgorzata Iwona Szynkowska-Jóźwik2
1Department of Bioinorganic Chemistry, Medical University of Lodz, Muszynskiego 1, 90-151 Lodz, Poland.
International journal of molecular sciences
|November 14, 2023
概括
银化合物显示出显著的抗微生物潜力,特别是在抗生素耐药性上升的情况下. 研究探索新的基于银的药物以提高疗效和基于药房的制剂,正在进行临床试验.
科学领域:
- 药用化学 医学化学
- 药理学 药理学是指药理学的学科.
- 微生物学 微生物学
背景情况:
- 银的历史用途用于治疗性质.
- 越来越多的微生物对抗生素的耐药性需要替代性抗菌剂.
- 银的独特的抗菌活性和有限的细菌耐药性.
研究的目的:
- 审查银,其盐及其复杂化合物的临床潜力.
- 概述银的历史医学和制药应用.
- 探索在药房中制备基于银的抗菌药膏的可能性.
主要方法:
- 关于银的临床应用和历史用途的文献综述.
- 协调化学的分析 在设计基于银的化合物方面取得的进展.
- 研究合成和表征新型含银物质.
主要成果:
- 银化合物表现出广泛的抗微生物活性,对抗抗生素耐药性至关重要.
- 通过协调化学设计的新型基于银的物质显示出增强的功效.
- 证明了抗微生物银膏的药房合成潜力.
结论:
- 基于银的化合物是传统抗生素的有希望的替代品,因为它们的疗效和耐药性较低.
- 正在进行的合成和表征研究可能会导致新的治疗应用.
- 银基抗菌剂的药房级准备是可行的,需要进一步调查.
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