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Updated: Jul 11, 2025

RhoC GTPase Activation Assay
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致癌性Gαq通过PDZ-RhoGEF激活了RhoJ

Rodolfo Daniel Cervantes-Villagrana1, Víctor Manuel Color-Aparicio1, Alejandro Castillo-Kauil1

  • 1Department of Pharmacology, Cinvestav-IPN. Av. Instituto Politécnico Nacional, Col San Pedro Zacatenco, Mexico City 07360, Mexico.

International journal of molecular sciences
|November 14, 2023
PubMed
概括

瘤性Gαq通过PDZ-RhoGEF激活RhoJ,这是皮膜黑色素瘤的一个新途径. 这个Gαq-PDZ-RhoGEF-RhoJ轴为Gαq驱动的癌症提供了新的治疗点.

关键词:
档案馆11 档案馆11这是PDZ-RhoGEF.在RhoJJ RhoJ芽的内皮细胞生长.瘤原性 Gαqq 的情况.

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