洋皮提取物之间的比较研究,自由和复杂的β-环氧,作为自然UV过器的化品配方
Mariana A Messias1,2, Sara M Ferreira1,2, Loleny Tavares3,4,5
1LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty de Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.
International journal of molecular sciences
|November 14, 2023
概括
洋皮提取物,富含奎尔素和白醇,提供了一个天然的紫外线过器替代品. 微封装化合物显示出高效率和稳定性,呈现出可持续的防晒成分.
科学领域:
- 自然产品化学 自然产品化学
- 化品科学 化品科学
- 材料科学 材料科学 材料科学
背景情况:
- 人们越来越担心合成紫外线过器对环境和健康的影响.
- 需要在防晒中找到可持续和环保的替代品.
- 洋皮 (OP) 作为生物活性化合物的潜在来源.
研究的目的:
- 从洋皮 (OP) 中提取和微封装生物活性化合物.
- 评估OP提取物及其微粒的光保护能力和抗氧化特性.
- 评估OP微粒作为化品配方中的天然紫外线过器的潜力.
主要方法:
- 从洋皮中提取生物活性化合物 (OP).
- 敏感化合物的分子含量,使用β-环氧素进行微封装.
- 高性能液体色谱 (HPLC-DAD) 用于化合物识别和量化.
- 阳光保护因子 (SPF) 评价,抗氧化能力测定和颗粒特征 (大小,多分散性).
- 制备O/W乳液,以测试微粒稳定性和随时间推移的性能.
主要成果:
- 克尔西和白醇被确定为OP提取物的主要成分.
- 微粒显示出高封装效率 (91.8%) 和有利的粒子特性 (31微米平均直径,2.09多分散性).
- 提取物和微粒具有显著的光保护能力 (可与合成紫外线过器相提并论) 和高抗氧化活性.
- 在O/W乳液中,微粒物在五周的时间内有效地保持了SPF值.
- 在不同地区的紫外线吸收证实了其作为广谱天然紫外线过器的潜力.
结论:
- 洋皮 (OP) 提取物,特别是其素和白醇含量,是天然紫外线过器的可行来源.
- 使用β-cyclodextrin进行微封装可以提高OP生物活性化合物的稳定性和有效性.
- OP衍生微粒为防晒应用提供了合成UV过器的可持续,环保的替代方案.
相关概念视频
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