饮食对生化成份的生物可用性的影响 香的活性成分 使用体外消化模型
Justyna Zagórska1, Karolina Pietrzak1, Wirginia Kukula-Koch2
1Department of Food and Nutrition, Medical University of Lublin, 4a Chodzki Str., 20-093 Lublin, Poland.
Foods (Basel, Switzerland)
|November 14, 2023
概括
食纤维显著提高了生的生物可用性.
科学领域:
- 药理学和营养科学 药理学和营养科学
- 食品化学和分析与分析.
背景情况:
- 生 (Zingiber officinale) 在全球范围内以其,药用和化品用途而闻名.
- 它的根茎含有丰富的生物活性多,包括因其健康益处而闻名的生和shogaols.
- 了解这些化合物的生物可用性对于优化它们对健康的影响至关重要.
研究的目的:
- 为了评估关键的生多的生物利用性 (6-生,8-生二,8-shogaol,10-生二).
- 评估不同饮食 (高纤维,标准,基本) 对多吸收的影响.
- 在体外模拟人类消化和小肠吸收过程.
主要方法:
- 利用体外消化模型来模仿生理消化过程.
- 使用高性能液体染色学-质谱法 (HPLC-MS) 进行定性分析.
- 应用高性能液体染色学 (HPLC) 用于生多的定量分析.
主要成果:
- 富含纤维的饮食显示,6-醇 (33.3%),8-二 (21.4%),8-二 (6.73%) 和10-二 (21.0%) 的生物可用性最高.
- 标准饮食和基本饮食显示,多的生物可用性显著降低.
- 例如,基本饮食产生的生物利用率为21.3%,5.3%,2.0%和1.0%的相应的化合物.
结论:
- 饮食成分,特别是纤维含量,严重影响生多的生物可用性.
- 富含纤维的饮食显著提高了有益的生化合物的吸收.
- 这些发现支持将生纳入高纤维饮食模式,以获得潜在的健康益处.
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