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肥胖妇女的瘦组织质量和肌肉功能之间的关系

Laurent Maïmoun^1,2, Elise Bourgeois^2,3, Chris Serrand⁴

¹Depatment of Nuclear Medicine, CHU Montpellier, 34295 Montpellier, France.

|November 14, 2023

概括

肥胖的老年女性经历了肌肉质量和肌肉功能的减少,增加了sarcopenic肥胖 (SO) 风险. 然而,即使在老年人中,SO的总体患病率仍然很低.

科学领域:

老年学是一门学科.
肥胖问题研究研究
肌肉生理学肌肉生理学

背景情况:

在肥胖个体中,瘦组织质量 (LTM) 随着年龄的增长而下降.
与衰老和肥胖相关的肌肉强度和功能变化尚未得到充分理解.
肥胖症 (SO) 的特点是随着肥胖而失去肌肉质量和力量.

研究的目的:

研究肥胖女性的LTM,脂肪质量 (FM),肌肉强度和肌肉功能的与年龄相关的变化.
为了确定这个人群中形肥胖 (SO) 的患病率.
探索LTM,肌肉力量和功能表现与肥胖女性衰老之间的关系.

主要方法:

使用DXA对383名肥胖妇女进行了LTM和FM的评估.
使用手握测试来测量肌肉力量.
用6分钟步行测试 (6MWT) 评估肌肉功能.

主要成果:

衰老导致LTM和FM的重新分配,体内增加和下肢损失,减少尾LTM指数.
肌肉的强度和功能随着年龄的增长显著下降.
低肌肉强度和功能的患病率分别为老年女性的22.8%和13.4%.
随着年龄的增长,SO的患病率增加,但即使在60岁以上的女性中,受影响女性的绝对数量仍然很低 (n ≤15).

结论:

肥胖女性的衰老与身体组成和身体表现的有害变化有关.
虽然年龄增加了SO风险因素,但肥胖女性的SO总体患病率很低.
尾LTM减少和肌肉性能下降有助于SO,但其发生在这个队列中是有限的.

关键词:

瘦身组织质量瘦身组织质量肌肉功能肌肉功能肌肉功能肌肉的力量肌肉的力量肌肉的力量身体表现身体表现身体表现萨尔科佩尼克肥胖症肥胖症患有肥胖症的女性.

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