解开社会孤立,厌食症,肉症和死亡率之间的复杂相互作用:从一个纵向研究的见解
1Fei-Yuan Hsiao, Ph.D., Professor and Director, Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Linsen S. Rd, Taipei 10050, Taiwan. Tel.: 886-2-33668787, E-mail: fyshsiao@ntu.edu.tw; Liang-Kung Chen, Professor, Center for Geriatrics and Gerontology, Taipei Veterans General Hospital, No. 201, Sec 2, Shih-Pai Road, Taipei 11217, Taiwan. Tel: +886-2-28757830; Fax: +886-2-28757711;
The journal of nutrition, health & aging
|November 14, 2023
概括
社会孤立与老年人的厌食症和肉症有关. 结合起来,这些情况显著增加了长期死亡风险,突出了需要进行干预的需要.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 社会孤立是一种严重的老年综合征,具有不良的预后影响.
- 它经常与其他老年综合征同时发生,使健康状况恶化.
- 了解它在衰老厌食症和肉症中的作用对于老年人健康至关重要.
研究的目的:
- 在老年人中调查社会孤立与厌食症或肉症之间的关联.
- 检查社会隔离,厌食症和肉病对长期死亡率的影响.
- 确定这些疾病对所有原因死亡率的协同效应.
主要方法:
- 利用了台湾长度老龄研究 (TLSA) 的数据,这是一个全国代表的队列.
- 从1999年到2015年,分析了来自50岁以上的3762名参与者的数据.
- 使用后勤回归和Cox比例危险模型来评估关联和死亡风险.
主要成果:
- 在老年人中,社会隔离与厌食症 (aOR 1.46) 和肉症 (aOR 1.35) 有显著的关联.
- 社会孤立与厌食症或肉症的结合显著增加了所有原因的死亡风险 (aOR 1.65).
- 仅仅社会孤立就显示出与长期死亡风险的边界关联.
结论:
- 社会孤立与中老年人和老年人的厌食症和肉症密切相关.
- 它显著加剧了与衰老厌食症和肉症相关的死亡风险.
- 解决社会隔离对于改善健康状况和降低这一群体的死亡率至关重要.
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