通过住院瘤老年患者的多组件运动计划来定制功能衰退的预防:随机临床试验的研究协议
N Martínez-Velilla1, V Arrazubi, F Zambom-Ferraresi
1Nicolas Martínez-Velilla, PhD, Department of Geriatric Medicine, Hospital Universitario de Navarra, Irunlarrea 3, 31008 Pamplona, Spain, Nicolas.martinez.velilla@navarra.es, Twitter: @martinezvelilla.
The journal of nutrition, health & aging
|November 14, 2023
概括
这项研究调查了住院的老年癌症患者的炼计划. 这项干预旨在改善身体功能,但由于COVID-19大流行,招聘挑战出现了.
科学领域:
- 老年瘤学 老年瘤学
- 康复医学 康复医学 康复医学
- 临床试验 临床试验
背景情况:
- 癌症不成比例地影响着老年人,带来了独特的诊断和治疗挑战.
- 癌症患者的住院治疗,特别是老年人,往往涉及到长时间的床上休息,增加了肉症和残疾的风险.
- 癌症老年人群需要专门的护理来缓解与治疗相关的疾病.
研究的目的:
- 评估多组分运动干预措施在改善因瘤科急性病症住院的老年人功能能力方面的有效性.
- 评估干预对二次结果的影响,包括认知功能,情绪,生活质量和身体力量.
- 为癌症老年患者住院协议的潜在变化提供证据.
主要方法:
- 一项随机对照试验协议,涉及240名65岁及以上的住院患者.
- 干预组接受了为期4天的多组分运动计划 (每天2次);对照组接受了通常的医院护理.
- 主要终点:功能能力的变化 (短期身体性能电池);次要终点:认知/情绪状态,生活质量,力量,疼痛,营养,停留时间,跌倒,再入院和3个月死亡率.
主要成果:
- 由于COVID-19大流行,没有达到招聘目标.
- 在瘤老年患者中观察到的反应与先前对因医疗原因住院的老年人进行的研究有显著差异.
- 描述了招募患者的基础数据.
结论:
- 该研究方案是为了测试有关瘤老年患者运动益处的假设而制定的.
- 如果成功,这些发现可能会支持在瘤老年人住院治疗中转向个性化炼计划.
- 需要进一步的研究来克服招聘障碍,并确认干预的有效性.
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