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Updated: Jul 11, 2025

Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells
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Mechanical Stimulation-induced Calcium Wave Propagation in Cell Monolayers: The Example of Bovine Corneal Endothelial Cells

Published on: July 16, 2013

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释放ATP的panexin通道被 lysophospholipids 封闭

Erik Henze, Russell N Burkhardt, Bennett W Fox

    bioRxiv : the preprint server for biology
    |November 14, 2023
    PubMed
    概括

    Lysophospholipids 激活泛素通道,使细胞通过腺三酸盐 (ATP) 释放进行通信. 这一发现将脂质代谢与免疫信号联系起来,影响炎症和细胞反应.

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    Real-time Live-cell Flow Cytometry to Investigate Calcium Influx, Pore Formation, and Phagocytosis by P2X7 Receptors in Adult Neural Progenitor Cells11:47

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    ATP is a highly unstable molecule. Unless quickly used to perform work, ATP spontaneously dissociates into ADP and inorganic phosphate (Pi), and the free energy released during this process is lost as heat. The energy released by ATP hydrolysis is used to perform work inside the cell and depends on a strategy called energy coupling. Cells couple the exergonic reaction of ATP hydrolysis with endergonic reactions, allowing them to proceed.
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