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Updated: Jul 11, 2025

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在MYC-FBW7基突变中的生殖点突变引发了血液形成恶性瘤

Brian Freie1, Patrick A Carroll1, Barbara J Varnum-Finney2

  • 1Basic Sciences Division, Fred Hutchinson Cancer Center, Seattle WA, USA.

bioRxiv : the preprint server for biology
|November 14, 2023
PubMed
概括

在小鼠中,MYC基因 (MYC-T58A) 的单点突变导致血液生成原体的自我更新增加,导致淋巴瘤和白血病. 这突出了MYC的优势.

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