中间叶功能网络架构支持老年人的睡眠相关的情感记忆处理
Miranda G Chappel-Farley1,2, Jenna N Adams1,2, Richard F Betzel3
1Department of Neurobiology and Behavior, University of California Irvine, Irvine CA, 92697, USA.
bioRxiv : the preprint server for biology
|November 14, 2023
概括
睡眠期间大脑网络的更大整合支持情感记忆的保留. 海马和杏仁体的活动影响了这个过程,影响了记忆的巩固和回忆.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 网络科学 网络科学
背景情况:
- 记忆的巩固,特别是对情感内容的巩固,依赖于睡眠期间的海马-桃体相互作用.
- 非快速眼动慢波睡眠 (NREM SWS) 对于重新激活海马索引和绑定皮质信息至关重要.
研究的目的:
- 调查脑网络模块化和中心性的图形理论测量是否与记忆巩固理论一致.
- 确定网络组织,情感记忆保留和睡眠振荡之间的关系.
主要方法:
- 应用图形理论分析睡眠期间的大脑功能网络.
- 利用集中性和模块化措施来量化网络集成和分离.
- 与夜间情感记忆保留和睡眠振荡模式相关联的网络属性.
主要成果:
- 增加网络集成与在NREM SWS期间对情绪记忆的夜间保留增加相关.
- 较高的海马和杏仁体对网络组织的影响预测了更好的情感记忆保留.
- 与特定的睡眠振荡相关的中心性指标对于记忆巩固至关重要.
结论:
- 通过图形理论评估的大脑内在网络连接,可以预测大脑对情感记忆处理的能力.
- 网络集成和像海马体和杏仁体这样的关键大脑区域的影响对于睡眠期间的情感记忆巩固至关重要.
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