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Updated: Jul 11, 2025

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解码异质单细胞扰乱反应的解码

Bicna Song1,2, Dingyu Liu3,4, Weiwei Dai5,6

  • 1Center for Genetic Medicine Research, Children's National Hospital, Washington DC, USA.

bioRxiv : the preprint server for biology
|November 14, 2023
PubMed
概括

一个新的扰动反应得分 (PS) 量化了单细胞对遗传扰动的反应. 这种方法揭示了剂量反应模式,并确定了细胞异质性的生物驱动因素,推动了生物发现.

关键词:
基于CRISPR的基因乱是基因乱.这就是 Perturb-seqq.计算模型是一种计算模型.一个单细胞RNA-seqq.

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