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Updated: Jul 11, 2025

Simple and Rapid Method to Obtain High-quality Tumor DNA from Clinical-pathological Specimens Using Touch Imprint Cytology
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在中国大人口瘤中高度活跃的突变特征的表征

Aaron Chevalier1,2, Tao Guo1,3, Natasha Q Gurevich1,2

  • 1Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts.

medRxiv : the preprint server for health sciences
|November 14, 2023
PubMed
概括

这项研究分析了中国癌症患者的突变特征,发现与西方人群的相似之处,但也发现了独特的模式. 这些发现增强了对东方人口癌症发展的理解.

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Loss of Tumor Suppressor Gene Functions01:12

Loss of Tumor Suppressor Gene Functions

Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
When the tumor suppressor genes develop mutations or are lost, cells start growing out of control, leading to cancer. However, a single functional copy of the tumor suppressor gene is enough for the cells to maintain their normal functions and cell...
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