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Updated: Jul 26, 2026

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination
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Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination

Published on: July 4, 2007

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评估Plasmodium falciparum遗传学的性能,以推断国家疟疾控制计划在塞内加尔报告的发病率

Wesley Wong1, Stephen F Schaffner2, Julie Thwing3

  • 1Harvard T. H. Chan School of Public Health.

Research square
|November 14, 2023
PubMed
概括

对Plasmodium falciparum寄生虫菌株的遗传监测可以准确地推断疟疾发病率,当每年每1000人传播超过10例时. 在这个门以下,遗传指标可能无法可靠地预测进口影响导致的发病率.

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...