人口变化对南非结核病易感性的强烈影响
Oshiomah P Oyageshio1, Justin W Myrick2, Jamie Saayman3
1Center for Population Biology, University of California, Davis, Davis, CA 95616, USA.
medRxiv : the preprint server for health sciences
|November 14, 2023
概括
男性的性别,年龄,社会经济地位和出生地相互作用显著增加了南非的结核病 (TB) 风险. 这些因素,而不是吸烟或酒精,是北开普省结核病的主要驱动因素.
科学领域:
- 流行病学 流行病学
- 遗传学 是一个遗传学.
- 公共卫生 公共卫生
背景情况:
- 南非面临着高结核病 (TB) 负担,大多数病例没有同时感染艾滋病毒.
- 北开普省的结核病发病率极高,人口密度低,使其成为研究不足的地区.
结论:
- 在这个南非队列中,结核病的流行病学风险因素与全球人口不同.
- 相互作用效应突出显示了变化的SES和流动性对结核病风险的影响.
- 鉴定到的风险因素解释了结核病例/对照病例状态变异的16%.
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