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多回声获取和热剥离有助于精确的功能成像

Julia Moser¹, Steven M Nelson^1,2, Sanju Koirala^1,3

¹Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.

bioRxiv : the preprint server for biology

|November 14, 2023

概括

诸如多回声采集和NORDIC denoising等新方法改善了成人和儿童的精确功能映射. 这些技术提高了脑成像数据的质量,这对于理解大脑发育组织至关重要.

科学领域:

神经科学是一个神经科学.
发展生物学发展生物学
医疗成像医学成像

背景情况:

精密功能映射 (PFM) 提供了对成人大脑组织的洞察.
了解大脑功能组织的发育变化是有限的.
在发育过程中高可塑性需要先进的神经成像方法.

研究的目的:

调查多回声 (ME) 采集和NORDIC对精密fMRI的否定.
评估这些方法在成年人,儿童和婴儿中的有效性.
改进用于发育神经成像的数据采集,处理和分析.

主要方法:

应用ME fMRI数据采集和降噪与分布校正 (NORDIC) 的PCA.
利用了成人,儿童和婴儿参与者的精确fMRI数据.
评估时间信号噪声比 (tSNR) 和功能连接可靠性.

主要成果:

ME和NORDIC在成年人中改善了SNR和连接可靠性.
在成年人和发育样本中,NORDIC 消毒益处是一致的.
婴儿表现出明显的T2*放松时间,影响了ME数据的优化.

结论:

ME和NORDIC是对不同年龄组的PFM有前途的方法进步.
这些方法提高了发育期fMRI数据的质量.
需要进一步的研究来优化婴儿神经成像的ME获取.

关键词:

发育神经成像发育神经成像精确的功能映射精确的功能映射大脑发育大脑的发育大脑的发展方法的进步方法的进步.多个回声的多个回声新生儿们的新生儿

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