多细胞生长作为一个动态的细胞网络
Piyush Nanda1,2, Julien Barrere2, Thomas LaBar2
1Program in Biological and Biomedical Sciences, Harvard Medical School, Boston, MA 02115, USA.
bioRxiv : the preprint server for biology
|November 14, 2023
概括
多细胞酵母群根据细胞分裂和连接速率生长和分解. 接吻数和生长速度差异控制了群的大小和组成,为早期多细胞发育提供了洞察力.
科学领域:
- 细胞生物学 细胞生物学
- 发育生物学是发展生物学.
- 数学建模的数学建模
背景情况:
- 在发芽的酵母中,细胞在没有分离的情况下分裂,形成多细胞.
- 集群大小和细胞组成是关键的表型.
- 细胞特征和这些表型之间的定量关系尚未得到充分理解.
结论:
- 一些细胞特征在数量上控制多细胞集群表型.
- 这些发现揭示了多细胞的演变.
- 细胞组成的变化与体细胞的平均分数相反相关.
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