在 орто型肝移植中,手术期间大量输血的预测因素
Mohamed Alhamar1, Ajna Uzuni1, Harshita Mehrotra1
1Department of Pathology and Laboratory Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
Transfusion
|November 14, 2023
概括
鉴定了在正体肝移植 (OLT) 中大规模输血的预测因素. 以前的腹部手术,接受者的血红蛋白,MELD得分和缺血时间预测了输血需求,有助于血液银行库存管理.
科学领域:
- 移植手术 移植手术
- 肝病学 肝病学是一种肝病学.
- 输血医学 输血医学
背景情况:
- 正位肝移植 (OLT) 需要大量的输血,挑战血液银行库存.
- 识别大量输血的预测因素对于积极的库存管理和及时的患者护理至关重要.
研究的目的:
- 评估在接受OLT的患者手术期间大量输血的预测因素.
- 为血液银行策略提供信息,以管理OLT患者的输血需求.
主要方法:
- 2007-2017年970名OLT患者的回顾性分析,不包括重复移植.
- 大量输血被定义为手术期间≥10个单位的红血细胞 (RBC).
- 对人口,移植前实验室,捐赠者和手术内变量的多变量分析.
主要成果:
- 大规模输血发生在12.3%的OLT患者中.
- 预测因素包括先前的腹部手术,接受者的血红蛋白,末期肝病模型 (MELD) 评分,冷热缺血时间和手术持续时间.
- 在输血的红细胞单位和血/血小板单位之间发现了显著的相关性.
结论:
- 以前的腹部手术,接受者的血红蛋白,MELD得分和缺血时间是OLT大规模输血的关键预测因素.
- 这些发现可以更好地预测和管理对OLT的血液产品需求.
- 优化输血管理可以改善患者的治疗结果和资源分配.
相关概念视频
Kidney Transplant II: Surgical Procedure
20
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
20
Kidney Transplant I: Introduction
14
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
14
Tissue Transplantation
376
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
376
Blood Transfusion
575
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
575


