经受第三线治疗的耐火性过活膀妇女的液体摄入行为
Kelley Zhao1, Arshia Aalami Harandi1, Jennifer Ramgopal2
1Department of Urology, Stony Brook University Hospital, Stony Brook, New York, USA.
Neurourology and urodynamics
|November 14, 2023
概括
在患有耐火性过度活动膀 (OAB) 的女性中,总体液体摄入量与尿路症状的相关性较弱. 像吸烟和BMI这样的生活方式因素与OAB症状的联系比液体摄入更强烈.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 妇女健康 妇女健康
- 腎臟病學 (nephrology) 是一種醫學專業.
背景情况:
- 流体摄入与尿路症状有关,但其对女性耐火过活膀 (OAB) 的具体影响仍未得到充分研究.
- 耐火性OAB可能涉及独特的病理生理机制,需要对生活方式因素 (如流体消耗) 进行调查.
研究的目的:
- 为了检查流体摄入量,流体摄入行为和被诊断患有耐火性过活膀 (OAB) 的妇女的尿路症状之间的关系.
- 在这个患者群体中,确定液体消耗模式和下泌尿道症状 (LUTS) 的严重程度之间的潜在相关性.
主要方法:
- 一项前性横截面研究,涉及126名接受第三线OAB治疗的女性.
- 使用排泄日记来评估液体摄入量和行为;用国际商下尿道症状失禁问卷 (ICIQ-FLUTS) 来测量尿道症状.
- 统计分析包括斯皮尔曼等级相关性和千平方测试,以评估液体摄入量和症状严重程度之间的关系.
主要成果:
- 每日总体液体摄入量 (平均2567.0毫升) 在治疗组 (onabotulinumtoxinA,部神经刺激,圣节神经调节) 中没有显著差异.
- 在总液体摄入量和更糟糕的填充类型LUTS (r=0.241,p=0.007) 之间发现了微弱的相关性;与咖啡因摄入量没有观察到任何关联.
- 虽然52%的参与者限制了饮用液体,但这种行为与LUTS严重程度无关. 目前的烟草使用 (p<0.001) 和较高的BMI (r=0.351,p<0.001) 与分别增加的LUTS和失禁症状正相关.
结论:
- 液体摄入量似乎与耐火性OAB的妇女的症状有很小的关系.
- 烟草使用和体重指数 (BMI) 等生活方式因素在这个队列中与尿路症状有更显著的关联.
- 需要进一步的研究来探索OAB治疗期间的行为变化如何影响治疗结果.
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