老年乳腺癌:分期,分子替代物和治疗. 一个审查和元分析
Vasco C Fonseca1, Zacharoula Sidiropoulou2
1Department of Oncology, Hospital Centre of West Lisbon, Portugal.
Aging and disease
|November 14, 2023
概括
老年乳腺癌患者需要量身定制的治疗方法,而不是一种适合所有人的方法. 适应治疗决策和考虑独特的分子概况对于70岁以上女性的最佳护理至关重要.
科学领域:
- 在瘤学瘤学.
- 老年医学 老年医学
背景情况:
- 乳腺癌 (BC) 是全球女性的主要癌症.
- 治疗决策取决于年龄,病期和瘤分子亚型.
研究的目的:
- 为70岁以上的女性提供BC分期,分子代孕和治疗的最新概述.
- 综合 2013-2023 年的证据.
主要方法:
- 按照PRISMA指导方针和PICO框架进行系统审查.
- 在多个数据库中进行了搜索 (科学网,PubMed,MEDLINE,Scopus).
- 使用混合方法评估工具进行质量评估;使用RevMan 5.4.4进行元分析.
主要成果:
- 包括17篇文章,代表了最初4151.6名患者中的39906名患者.
- 在老年患者中确定了不同的分子代谢物.
- 外科手术成为首选的治疗选择.
结论:
- 老年乳腺癌患者需要个性化治疗策略.
- 由于不同的医疗保健系统,全球存在治疗差异.
- 建议治疗决策预约和遵守指南.
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