变化体质指数和事件轻度认知障碍在非洲裔美国老年人中
Adrienne T Aiken-Morgan1,2, Ana W Capuano3,4, Robert S Wilson3,4
1Campbell University Divinity School, Campbell University, Buies Creek, North Carolina, USA.
概括
在老年人中,轻度认知障碍 (MCI) 诊断后,身体质量指数 (BMI) 降低的速度更快. 高等教育与MCI诊断后的BMI下降加速有关.
科学领域:
- 老年学是一门学科.
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 以前的研究将老年人BMI下降与负面的健康结果联系在一起,包括轻度认知障碍 (MCI) 和痴呆症.
- 然而,教育或发展MCI对BMI轨迹的影响仍未得到充分研究.
研究的目的:
- 在患有MCI的老年人中描述BMI变化轨迹.
- 调查教育对这些BMI轨迹的影响.
主要方法:
- 来自少数民族衰老研究研究 (MARS) 队列的纵向数据的分析.
- 包括436名年长的非裔美国人参与者,在基线没有认知障碍.
- 利用零碎线性混合效应模型来分析BMI随时间的变化,考虑到MCI诊断和教育水平.
主要成果:
- 随着时间的推移,BMI显著下降 (B=-0.20,p<.001).
- 在MCI诊断后观察到更快的BMI下降 (额外下降B=-0.15,p=.019).
- 高等教育与较低的基线BMI和较慢的初始BMI下降有关,但MCI诊断后的下降速度更快.
结论:
- 诊断MCI与BMI的加速下降有关.
- 高等教育水平与MCI诊断后的BMI下降速度更快有关.
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