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Updated: Jul 11, 2025

Functional Characterization of Na+/H+ Exchangers of Intracellular Compartments Using Proton-killing Selection to Express Them at the Plasma Membrane
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立体选择性抑制高和低亲和率有机阴离子载体

Lukas Gebauer1, Ole Jensen1, Muhammad Rafehi1

  • 1Institute of Clinical Pharmacology, University Medical Center Göttingen, D-37075 Göttingen, Germany.

Molecular pharmaceutics
|November 14, 2023
PubMed
概括

药物反体对有机阴离子载体 (OCT) 和单胺载体 (MAT) 具有不同的选择性. 虽然OCT3表现出高的立体选择性,但大多数性药物表现出轻微的抑制,这表明临床药物相互作用风险有限.

关键词:
药物的反体是药物的反体.有机阴离子输送器 有机阴离子输送器溶液载体是溶解物质的载体.立体选择性的立体选择性.运输器抑制的抑制.

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