Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Acute Respiratory Failure-V01:29

Acute Respiratory Failure-V

143
The treatment for acute respiratory failure varies based on factors like the underlying cause, overall health, and severity. A collaborative healthcare team is essential for early detection, often through arterial blood gas analysis. Identifying the cause is the primary goal, with treatment strategies adjusted for ventilation/perfusion (V/Q) mismatch, shunting, or diffusion impairment.
Ensure that patients are monitored continuously for their response to therapy, including changes in...
143
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

190
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
190
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

249
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
249
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

160
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
160
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

218
Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...
218
Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

15
Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
15

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Physiological and clinical effects of selected airway clearance techniques in mechanically ventilated adult ICU patients: a systematic review and synthesis without meta-analysis.

Critical care (London, England)·2026
Same author

ECMO for patients with obesity: evidence and practice.

Intensive care medicine·2026
Same author

Regional gas exchange evaluation during ex vivo lung perfusion in a swine model of localized lung dysfunction.

Animal models and experimental medicine·2026
Same author

Definition and prognostic value of response to prone positioning in ARDS: a systematic review and meta-analysis.

Critical care (London, England)·2026
Same author

Parenting, pregnancy and work-family balance in intensive care medicine: an ESICM survey and a call for action.

Intensive care medicine·2026
Same author

Early trajectories of pulmonary hemodynamics in ARDS patients undergoing V-V ECMO: key determinants and prognostic impact.

Critical care (London, England)·2026

相关实验视频

Updated: Jul 11, 2025

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

411

目前关于体外呼吸器支的知识缺口.

Tommaso Tonetti1,2, Alberto Zanella3,4, David Pérez-Torres5

  • 1Department of Medical and Surgical Sciences (DIMEC), Alma Mater Studiorum-University of Bologna, Bologna, Italy.

Intensive care medicine experimental
|November 14, 2023
PubMed
概括

外体生命支持 (ECLS),包括静脉静脉外体膜氧化 (V-V ECMO) 和外体二氧化碳去除 (ECCO2R),提供先进的呼吸支持. 时间,设备和管理方面的挑战需要持续的研究,以获得最佳的患者结果.

关键词:
严重的呼吸衰竭是急性呼吸衰竭.气体交易所 气体交易所肺部保护性通风器的使用在V-V ECMO ECMO中使用.

更多相关视频

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

317
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

12.5K

相关实验视频

Last Updated: Jul 11, 2025

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting
08:53

Artificial Lung Device Priming for In Situ Fiber Bundle Surface Grafting

Published on: March 28, 2025

411
Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting
03:40

Point-of-Care Ultrasound for Peripheral Veno-Arterial Extracorporeal Membrane Oxygenation Without Left Ventricular Venting

Published on: January 17, 2025

317
Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse
06:41

Veno-Venous Extracorporeal Membrane Oxygenation in a Mouse

Published on: October 24, 2018

12.5K

科学领域:

  • 关键护理医学 关键护理医学
  • 呼吸系统生理学 呼吸系统生理学
  • 生物医学工程 生物医学工程

背景情况:

  • 急性呼吸衰竭需要超越常规通风的先进支持.
  • 静脉静脉外体膜氧化 (V-V ECMO) 和外体二氧化碳去除 (ECCO2R) 是ECLS的关键方式.
  • 目前的ECLS技术面临尺寸,耐用性和效率方面的局限性.

研究的目的:

  • 为急性呼吸衰竭提供V-V ECMO和ECCO2R的全面审查.
  • 讨论ECLS的临床应用,挑战和未来方向.
  • 突出ECLS技术和管理的研究和开发领域.

主要方法:

  • 关于V-V ECMO和ECCO2R的当前文献的审查.
  • 对氧化器和ECLS设备的技术进步进行分析.
  • 讨论临床管理策略,包括抗凝药和药理动力学.

主要成果:

  • 通过改善气体交换和减少肺部工作量,V-V ECMO有效治疗严重的ARDS.
  • 在中度ARDS和COPD恶化的情况下,ECCO2R促进了超保护性通风,并减少了通风负荷.
  • 关键的挑战包括启动的最佳时间,设备创新,凝血管理和断奶协议.

结论:

  • 包括V-V ECMO和ECCO2R在内的ECLS是治疗严重呼吸衰竭的重要工具.
  • 持续的研究和技术进步对于克服当前ECLS的局限性至关重要.
  • 整合ECLS与其他器官支持 (体外器官支持 - ECOS) 是重症患者的未来方向.