肥胖对新诊断和复发的移除后心房动的影响:系统性审查和元分析
F Folli1, L Centofanti2, S Magnani3
1Department of Health Sciences, University of Milan, Via A. Di Rudinì 8, 20142, Milan, Italy. franco.folli@unimi.it.
Journal of endocrinological investigation
|November 14, 2023
概括
超重和肥胖增加了发展心房动 (AF) 的风险. 与男性相比,肥胖女性面临新诊断的AF风险更高,BMI增加对AF发病的影响更大.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 超重/肥胖和心房动 (AF) 的发展之间确立的联系.
- 关于AF发生与复发的差异影响的不确定性.
- 需要探索与身体质量相关的AF风险的性别特异性差异.
研究的目的:
- 为了比较体重不足和不同程度的肥胖对AF发作的影响.
- 为了评估体质对复发性移除后AF的影响.
- 在BMI类别中调查AF风险的潜在基于性别的差异.
主要方法:
- 在PubMed,Embase和Cochrane图书馆进行系统的文献搜索,截至2023年1月31日.
- 包括在不同BMI类别中报告AF频率的研究.
- 使用随机效应模型的元分析,遵循PRISMA指南.
主要成果:
- 分析了50项涉及超过1500万患者的研究.
- 在超重,肥胖和病态肥胖个体中,新诊断的AF显著增加.
- 肥胖和致病性肥胖患者表现出反复复发的AF的风险增加.
- 新诊断的AF在肥胖女性中比男性更为普遍.
结论:
- 体重指数 (BMI) 升高显著增加了心房的发病和复发的风险.
- 增加的BMI对AF发病的影响比对AF复发更为明显.
- 与肥胖男性相比,肥胖女性的新诊断AF发病率更高.
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