2000年至2020年皮质纤维素瘤突起体的发病率和生存结果:基于人口的回顾性队列分析
David D Xiong1,2, Jeremy S Bordeaux1,2
1Department of Dermatology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio.
概括
皮质纤维素瘤突起体 (DFSP) 发病率在2000年至2020年期间保持稳定. 高龄,男性性别,较大的瘤,较低的收入和下肢位置加重了生存率,而莫斯手术可以改善它.
科学领域:
- 在瘤学瘤学.
- 皮肤病学 皮肤病学
- 流行病学 流行病学
背景情况:
- 皮肤纤维瘤突起 (DFSP) 是一种罕见的皮肤癌.
- 最近DFSP发病率和存活率的趋势没有得到充分的记录.
研究的目的:
- 分析DFSP发病率在二十年中的变化.
- 确定影响DFSP患者整体和癌症特异性生存的因素.
主要方法:
- 使用监测,流行病学和最终结果 (SEER) 数据库 (2000-2020) 进行回顾性队列研究.
- 考克斯和细灰回归模型被用来评估生存结果.
主要成果:
- DFSP的发病率保持不变,大约为每百万人年4.6例.
- 与整体存活率较低相关的因素包括年龄较大,男性性别,较大的瘤大小,较低的收入和下肢位置.
- 莫斯手术表明整体生存率有所改善,而晚年和大瘤大小与更糟糕的DFSP特异性死亡率有关.
结论:
- 从2000年到2020年,国外外交政策部的发病率一直保持稳定.
- 随着年龄的增长,瘤大小,男性性别,低收入和瘤位置的增加,生存受到负面影响,但莫斯手术对生存有积极的影响.
- 年龄和瘤大小显著影响DFSP特异性死亡率.
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