开发一个综合的纵向数据集,以以患者为中心的结果测量与成本相关的药物不服药
James X Zhang1, David O Meltzer1,2,3
1Department of Medicine.
Medical care
|November 14, 2023
概括
与成本相关的药物不服药 (CRN) 影响了许多医疗保险受益人. 持久性CRN与抑郁症和年轻年龄有关,突出了针对性干预的需要.
科学领域:
- 医疗保健服务研究 医疗服务研究
- 老年学是一门学科.
- 药物经济学 药物经济学
背景情况:
- 与成本相关的药物不服药 (CRN) 是一个以患者为中心的关键结果.
- 追踪CRN的纵向研究很少,限制了对其时间模式的理解.
研究的目的:
- 为纵向CRN研究开发一个综合数据集.
- 描述CRN模式,并确定高风险医疗保险受益人的相关因素.
主要方法:
- 2000名高风险医疗保险受益人的队列在CRN上每季度进行8个季度 (2013-2018) 的调查.
- 数据集与医疗保险文件联系在一起,并开发了一个CRN指标 (持久,间歇,短暂).
- 顺序逻辑和逻辑模型评估了影响CRN和持久CRN的因素.
主要成果:
- 在1761名分析患者中,49.3%的患者至少经历过一次CRN;10%的CRN持久.
- 持久的CRN与较低的双重资格 (aOR=0.45) 和较高的抑郁症 (aOR=1.55) 相关.
- 年龄较小与较高的持续性和间歇性CRN相关;过渡性CRN与年龄无关.
结论:
- 持久性CRN影响了大量的患者群体,包括临终期患者.
- 进一步的研究是必要的,以了解年轻的医疗保险人群中的CRN行为模式,并告知干预措施.
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