伏尔沃迪尼亚是否与阴道微生物群的改变有关? : 一个系统的审查
Koray Gorkem Sacinti, Hosna Razeghian1, Yaseen Awad-Igbaria
1Ankara University School of Medicine, Ankara, Turkey.
Journal of lower genital tract disease
|November 14, 2023
概括
阴道微生物群似乎没有连贯地与vulvodynia (痛) 联系在一起. 目前的研究表明,这种情况和没有这种情况的女性之间的细菌组成没有显著差异.
科学领域:
- 妇科 妇科 妇科 妇科
- 微生物学 微生物学
- 妇女健康 妇女健康
背景情况:
- 无明确原因的阴道疼痛的特征是vulvodynia,显著影响生活质量.
- 由于治疗选择有限,了解vulvodynia的病因至关重要.
- 阴道微生物群在妇科疾病中的作用促使人们对其与vulvodynia的联系进行调查.
研究的目的:
- 系统地审查有关阴道微生物群和vulvodynia之间的关联的现有文献.
- 评估目前关于阴道微生物组在vulvodynia发展中的潜在作用的证据.
主要方法:
- 在主要数据库 (PubMed,Scopus,Web of Science等) 中进行了系统的文献搜索. 在2023年5月之前.
- 搜索术语包括"vulvodynia"",vestibulodynia"",microbiome"",microbiota"和"flora. "等等,这些术语也被广泛使用.
- 确定了八项病例控制研究,并使用纽卡斯尔-太华尺度对其质量进行了评估.
主要成果:
- 大多数研究都没有发现女性的阴道细菌组成的显著差异,vulvodynia和对照.
- 没有特定的细菌种群被始终确定与vulvodynia相关.
- 阴道微生物群多样性和vulvodynia之间的关系需要进一步调查.
结论:
- 阴道微生物群在vulvodynia中的作用仍然不清楚.
- 当前研究的横截面性质阻止了因果推理.
- 需要对更大,多样化的群体和先进技术进行进一步的研究,以阐明任何潜在的联系.
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