在接受结肠镜检查的老年患者中,肠道准备不足的预测因素:系统性审查和元分析
Yuanyuan Zhang1, Lining Wang2, Wenbi Wu3
1School of Medical and Health Engineering, Changzhou University, Changzhou 213000, Jiangsu, China.
老年人肠道准备不足与便秘,糖尿病和不良饮食遵守等因素有关. 解决这些风险因素可以改善老年患者的结肠镜检查结果.
科学领域:
- 胃肠病学 胃肠病学
- 老年医学 老年医学
- 临床研究 临床研究
背景情况:
- 老年人肠道准备质量的预测因素仍然不清楚.
- 目前的指导方针缺乏针对这一群体的具体建议.
研究的目的:
- 在接受结肠镜检查的老年患者中,确定肠道准备不足的独立风险因素.
- 为开发预测模型提供数据,以对肠道不良准备进行预测.
主要方法:
- 队列和横截面研究的系统审查和元分析.
- 搜索了多个数据库 (PubMed,Embase,科学网,CNKI,万芳,VIP) 截至2023年2月.
- 使用固定和随机效应模型,包括灵敏度分析和偏差评估的聚合赔率比率 (OR).
主要成果:
- 六项研究 (n=1553-2163) 确定了关键的危险因素.
- 显著的危险因素包括:以前的腹部手术 (OR=2.72),便秘 (OR=3.56),糖尿病 (OR=2.54),不遵守饮食 (OR=2.51),不完全的药摄入 (OR=2.43),以及不充分的运动 (OR=3.13).
结论:
- 三种并发症 (便秘,糖尿病,之前的手术) 和三个行为因素 (饮食不遵守,不完全的药摄入量,不充分的运动) 显著预测老年人肠道准备不足.
- 研究结果为临床实践和预测模型开发提供了宝贵的见解.
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