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在接受抗逆转录病毒治疗的艾滋病毒阳性患者中发病性脊髓炎:一系列病例
Maria Kitchen1, Irina Gasslitter1, Martin Gisinger1
1Department for Dermatology, Venerology, and Allergology, Medical University of Innsbruck, Innsbruck, Austria.
International journal of STD & AIDS
|November 14, 2023
概括
炎症性脊髓炎是一种脊髓感染,可发生在接受抗逆转录病毒疗法 (ART) 的艾滋病毒感染者中. 这项研究突出了病例,并强调了对这种严重疾病的风险因素的认识.
科学领域:
- 传染性疾病 传染性疾病
- 整形外科 整形外科 整形外科
- 艾滋病毒 医学 艾滋病毒 医学
背景情况:
- 在欧洲和北美,发烧性脊髓瘤炎的发病率正在上升.
- 在抗逆转录病毒疗法 (ART) 时代,艾滋病毒感染对脊髓炎风险的作用尚不清楚.
研究的目的:
- 在艾滋病毒感染者接受ART治疗并抑制病毒载荷的个体中调查发烧性脊髓瘤炎.
主要方法:
- 在6名艾滋病毒感染者接受ART治疗时,发生了7例发热性脊髓瘤炎事件的病例系列.
- 通过MRI和病原体隔离证实了诊断.
- 治疗包括手术和长时间的抗生素治疗.
主要成果:
- 所有患者都表现出严重的疼痛和炎症标志物升高.
- 金黄色葡萄球菌是最常见的病原体.
- 五名患者完全康复,一人死于多器官衰竭.
结论:
- 脊髓瘤炎可能越来越普遍在老年人与艾滋病毒,由于伴随性疾病.
- 艾滋病毒医生需要意识到这种感染和相关的危险因素.
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