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COVID-19的严重程度与胃肠道出血的风险有关
Shuji Hibiya1, Takashi Fujii2, Toshimitsu Fujii3
1Department of Gastroenterology and Hepatology, Tokyo Medical and Dental University, Tokyo, Japan.
冠状病毒疾病2019 (COVID-19) 的严重程度增加了胃肠道出血的风险. 患有严重或危急COVID-19的患者面临显著更高的风险,特别是下胃肠道出血.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- COVID-19严重程度和胃肠道 (GI) 出血之间的关系尚不清楚.
- 了解这种关联对于管理住院患者至关重要.
研究的目的:
- 为了调查COVID-19的严重程度是否是胃肠道出血的危险因素.
- 为了量化肠道出血的风险与COVID-19的严重程度相关.
主要方法:
- 对12044名住院COVID-19患者的回顾性队列研究 (2020年1月至2021年12月).
- 根据国家卫生研究院标准分类的COVID-19严重程度.
- 多变量后勤回归分析了COVID-19严重程度和GI出血发生之间的关联.
主要成果:
- 55名患者 (0.5%) 经历了胃肠道出血.
- 严重的COVID-19 (OR: 3.013) 和危急的COVID-19 (OR: 15.632) 显著增加了胃肠道出血的风险.
- 严重的COVID-19增加了下部胃肠道出血的风险 (OR:10.349),但不是上部胃肠道出血.
结论:
- COVID-19的严重程度与胃肠道出血的风险增加有关.
- 下胃肠道出血与严重的COVID-19特别相关.
- 患有严重或危急COVID-19的患者需要谨慎管理,因为胃肠道出血风险较高.
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