血尿素度与成人严重腹腔大动脉化有关:一个截面调查
1Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Scientific reports
|November 14, 2023
概括
在40岁以上的美国成年人中,较高的血尿 (BUN) 水平与严重腹腔大动脉化 (AAC) 的风险增加有关. 这一发现强调了BUN作为AAC风险评估的潜在指标.
科学领域:
- 心血管健康 心血管健康
- 腎臟病學 (nephrology) 是一種醫學.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 腹腔大动脉化 (AAC) 是血管疾病的标志物.
- 血液尿素 (BUN) 是功能的一种常见生物标志物.
- BUN和严重的AAC之间的关系需要进一步调查.
研究的目的:
- 研究血液尿素 (BUN) 和严重腹腔大动脉化 (AAC) 之间的相关性.
- 为了评估40岁及以上的美国成年人之间的这种关联.
主要方法:
- 来自NHANES 2013-2014数据集的2757名参与者的分析.
- 血液尿素 (BUN) 通过酶导率法测量.
- 严重的AAC定义为Kauppila分数≥6;使用多变量逻辑回归和受限立方线分析.
主要成果:
- 最高的BUN水平 (log2转换) 与严重AAC风险增加有显著的关联 (OR=1.77,95%CI 1.17-2.71).
- 在BUN和严重的AAC之间观察到一个反向的L形关联.
- 没有发现涉及BUN的显著相互作用.
结论:
- 血液尿素 (BUN) 和严重腹腔大动脉化 (AAC) 的风险之间存在正相关性.
- 升高的BUN可以作为成年人群中严重AAC的预测标记.
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