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Assessment of Vascular Function in Patients With Chronic Kidney Disease
Published on: June 16, 2014
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有风险的工作条件和慢性病
Rui Lan1, Yao Qin1, Xiangjun Chen1
1Department of Endocrinology, The First Affiliated Hospital of Chongqing Medical University, No.1 Youyi Street, Yuzhong District, Chongqing, 400016, China.
Journal of occupational medicine and toxicology (London, England)
|November 14, 2023
概括
职业暴露,如繁重的工作负载和轮班工作,增加慢性病 (CKD) 的风险. 负面的工作条件的结合显著提高了CKD风险,突出显示了工作场所干预的必要性.
科学领域:
- 职业健康 职业健康 职业健康 职业健康
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
背景情况:
- 工作场所的环境涉及到各种各样的暴露,任务和时间表.
- 职业暴露与慢性病 (CKD) 风险增加有关.
- 社会条件和职业因素的结合也可能影响CKD的发展.
研究的目的:
- 调查各种职业工作条件与CKD发病率之间的关联.
- 评估CKD多种不利工作条件的共同风险.
- 为了识别高风险的职业暴露,用于预防CKD.
主要方法:
- 对65,069名没有基线CKD的英国生物库参与者 (40-69岁) 的前性分析.
- 自主管理的调查问卷评估了职业热量,二手烟,轮班工作和重度工作负载.
- 考克斯的比例危险回归模型分析了工作条件和CKD发病率,并制定了风险评分.
主要成果:
- 沉重的工作负载 (HR 1.24),轮班工作 (HR 1.33) 和二手烟 (HR 1.13) 与增加CKD风险有显著的关联.
- 职业热量暴露显示出非显著的趋势,导致CKD风险增加 (HR 1.11).
- 综合工作条件风险评分显示,与CKD发病率存在显著的剂量依赖关联.
结论:
- 不利的工作条件,特别是结合起来,显著增加慢性病 (CKD) 的风险.
- 研究结果支持实施有针对性的工作场所干预措施,以减轻CKD的职业风险.
- 该研究为预防策略提供了基础,以应对联合职业危险和CKD.
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