在美国成年人中,食维生素C与腹腔大动脉化之间的关联
Jundi Jia1,2, Jie Zhang3, Qiao He4
1Graduate School, Beijing University of Chinese Medicine, Beijing, China.
Nutrition journal
|November 14, 2023
概括
饮食中摄入较高的维生素C与减少腹腔大动脉化 (AAC) 和降低血管疾病风险有关. 在美国成年人中,维生素C补充剂与AAC没有显著的关联.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 血管生物学 血管生物学
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因.
- 血管化,特别是腹腔大动脉化 (AAC),是心血管疾病事件的强烈预测因素.
- 维生素C摄入量和AAC之间的关联仍然不完全理解.
研究的目的:
- 检查美国成年人中饮食维生素C摄入量与腹腔大动脉化 (AAC) 之间的关系.
- 要区分食维生素C与维生素C补充剂对AAC的影响.
- 评估维生素C对发展AAC的风险的影响.
主要方法:
- 2013-2014年国家健康和营养检查调查 (NHANES) 数据的横截面分析.
- 包括2297名成年受试者,使用Kauppila (24分) 和Schousboe (8分) 尺度测量AAC.
- 权重多重回归分析和通用添加模型 (GAM) 用于评估饮食维生素C三位数和AAC分数/风险之间的关联,以及对维生素C补充剂的探索性分析.
主要成果:
- 饮食中摄入较高的维生素C显著与较低的AAC得分相关 (AAC-24:β = -0.338,P = 0.004;AAC-8:β = -0.132,P = 0.002).
- 饮食中增加的维生素C摄入量与患有AAC的风险降低相关 (OR = 0.807,P = 0.038).
- 在维生素C补充剂摄入量和AAC之间没有发现显著的关系.
结论:
- 饮食中的维生素C摄入量,但不是维生素C补充剂,与美国成年人的腹腔大动脉化 (AAC) 相反相关.
- 富含维生素C的饮食可能会提供对血管化和随后的心血管疾病的保护性益处.
- 对食维生素C在血管健康中的具体机制进行进一步的研究是有必要的.
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