评估在观察性研究中发现的药物管理错误的严重程度,使用有效可靠的方法
Lindemberg Assunção-Costa1, Charleston Ribeiro Pinto2, Juliana Ferreira Fernandes Machado3
1Department of Medicine, School of Pharmacy, Federal University of Bahia and National Institute for Phamaceutical Assistence and Pharmacoeconomy - INAFF, Rua Barão de Jeremoabo, 147, 2º andar, Campus Ondina, Salvador, Bahia, 40170-115, Brazil. lindemberg.rn@gmail.com.
Journal of pharmaceutical policy and practice
|November 15, 2023
概括
这项研究评估了教学医院的药物错误,发现大多数是中度的. 然而,潜在的严重药物错误率高于先前的研究,表明需要改进安全策略.
科学领域:
- 医疗保健的质量和安全
- 临床药房 临床药房
- 患者安全研究 患者安全研究
背景情况:
- 关于药物错误严重性的流行病学数据有限.
- 缺乏识别药物管理错误的标准化和适当的严重性评估工具.
- 这项研究解决了在教学医院使用直接观察评估潜在错误严重性的需要.
研究的目的:
- 评估通过直接观察发现的药物管理错误的潜在严重程度.
- 通过使用经过验证的评分系统,提供对错误严重性的定量衡量.
- 为了识别潜在的严重药物错误的模式.
主要方法:
- 用一个经过验证的10分级来评估药物管理错误的潜在严重程度.
- 203个先前识别的错误被分类为67种独特的错误类型.
- 一个由医生,护士和药剂师组成的小组评估了每个错误类型的严重程度.
主要成果:
- 8.8%的错误被归类为轻微错误,82.8%为中度错误,8.4%为严重错误.
- 技术错误占潜在严重错误的41%.
- 胰岛素经常涉及潜在的严重错误,其中53%涉及静脉注射.
结论:
- 专家小组认为大多数药物错误的潜在严重程度是中等的.
- 观察到的潜在严重药物错误的频率超过了使用类似方法的先前研究的频率.
- 显然需要实施策略来减少严重药物错误的发生.
相关概念视频
Systematic Error: Methodological and Sampling Errors
1.5K
In the case of systematic errors, the sources can be identified, and the errors can be subsequently minimized by addressing these sources. According to the source, systematic errors can be divided into sampling, instrumental, methodological, and personal errors.
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
Sampling errors originate from improper sampling methods or the wrong sample population. These errors can be minimized by refining the sampling strategy. Defective instruments or faulty calibrations are the sources of instrumental...
1.5K
Errors occurring during blood pressure monitoring
740
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
Several factors...
740
Observational Studies
8.7K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.7K
Pharmacovigilance
860
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
860
Random and Systematic Errors
11.0K
Scientists always try their best to record measurements with the utmost accuracy and precision. However, sometimes errors do occur. These errors can be random or systematic. Random errors are observed due to the inconsistency or fluctuation in the measurement process, or variations in the quantity itself that is being measured. Such errors fluctuate from being greater than or less than the true value in repeated measurements. Consider a scientist measuring the length of an earthworm using a...
11.0K
Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K


