标准化腹腔透析 (PD) 培训与PD相关感染的常规护理的多中心,务实,集群随机,受控试验 (TEACH-PD试验):试验协议
Josephine S F Chow1,2,3,4,5, Neil Boudville6,7, Yeoungjee Cho8,9
1South Western Sydney Local Health District, Liverpool, NSW, Australia. Josephine.Chow@health.nsw.gov.au.
Trials
|November 15, 2023
概括
提高腹腔透析结果的有针对性的教育方法 (TEACH-PD) 试验调查了标准化的培训是否可以减少腹腔透析 (PD) 感染. 这种方法旨在通过实施ISPD指南来改善PD的可持续性和患者的结果.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床试验 临床试验
- 预防传染病 预防传染病
背景情况:
- 腹腔透析 (PD) 相关的感染是PD治疗长期成功的一个主要挑战.
- 缺乏标准化的PD培训课程,可能会导致感染率上升.
- 提高腹腔透析结果的有针对性的教育方法 (TEACH-PD) 试验解决了这一差距.
研究的目的:
- 评估基于国际腹腔透析学会 (ISPD) 准则的标准化培训课程,与通常的培训相比,是否可以减少PD相关的感染.
- 评估标准化培训对各种次要结果的影响,包括感染相关的导管切除,转移到血液透析,生活质量,住院和死亡率.
主要方法:
- 一个基于注册的,务实的,开放的标签,多中心,双国,集群随机对照试验,涉及澳大利亚和新西兰的42个PD治疗单位.
- 在2019年7月至2023年6月期间招募新的PD培训成年患者 (≥18岁).
- 将集群随机分配到标准化的TEACH-PD培训或通常的培训实践中,随时跟踪至少12个月 (平均2年).
主要成果:
- 主要结局:任何PD相关感染 (出口部位,道或腹膜炎) 首次发生的时间.
- 二次结果:个别的感染组件,导管切除,转移到血液透析,生活质量,住院治疗,全因死亡和成本效益.
- 从ANZ透析和移植注册表 (ANZDATA) 和NZPD注册表收集的数据.
结论:
- TEACH-PD试验旨在提供高确定性证据,证明基于ISPD指南的标准化PD培训课程的有效性.
- 结果将为PD护士培训师和患者提供最佳实践信息,以预防PD相关的感染.
- 该研究旨在通过基于证据的培训来提高PD的可持续性和改善患者护理.
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