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Updated: Jul 11, 2025

Mimicking and Manipulating Pancreatic Acinar-to-Ductal Metaplasia in 3-dimensional Cell Culture
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Published on: February 11, 2019

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瘤性KRAS,素4和Activin A介导的纤维细胞激活合作促进PanIN的启动

Chun-Mei Hu1, Chien-Chang Huang1,2, Min-Fen Hsu1

  • 1Genomics Research Center, Academia Sinica, Taipei, 11529, Taiwan.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 15, 2023
PubMed
概括

瘤性KRAS突变本身不会导致胰腺癌前体病变. 新的研究表明,Muc4过度表达和纤维细胞相互作用是关键因素,为早期胰腺管道腺癌的诊断和治疗提供了目标.

关键词:
这是一个很棒的体验. 克拉斯克拉斯克拉斯这就是 Muc4 Muc4.帕尼恩 (PanININ) 是一家专业的企业.活性蛋白 A 是一种活性蛋白.αSMA+ 纤维细胞.

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