对于结肠直肠癌查的不令人满意的便免疫化学测试:患病率,原因和随后的测试
Po-Hong Liu1, Rasmi G Nair2, Celette Sugg Skinner2,3
1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
概括
十分之一的人有不令人满意的便免疫化学测试 (FIT),通常是由于患者相关的问题,如样本采集. 不到一半完成了后续测试,突出了结直肠癌查效率的差距.
科学领域:
- 胃肠病学 胃肠病学
- 公共卫生 公共卫生
- 医疗保健服务研究 医疗服务研究
背景情况:
- 便免疫化学测试 (FIT) 是结直肠癌查的一个关键工具.
- 了解FIT处理的问题,如样本问题,对于选计划的成功至关重要.
研究的目的:
- 确定不令人满意的FIT结果的流行率和原因.
- 确定与不令人满意的FIT和随后的测试相关的因素.
- 在初始不满意的FIT之后,评估测试完成率.
主要方法:
- 对50-74岁的平均风险个体进行了回顾性队列研究.
- 在大型卫生系统中分析2010-2019年FIT完成数据.
- 多变量后勤回归用于识别与不令人满意的FIT和后续测试相关的因素.
主要成果:
- 10.2%的FIT是不令人满意的,主要是由于样本不足 (51%) 或标签不足 (27%).
- 不满意的FIT与男性性别,黑人种族,西班牙语,医疗补助保险和以邮件为基础的FIT交付有关.
- 只有41%的不满意FIT的个人在15个月内完成了随后的测试.
结论:
- 很大一部分FIT是不令人满意的,通常是由于患者相关的因素.
- 在不满意的FIT后,随访测试率低表明需要进行干预.
- 解决样本采集和标签问题可以提高结直肠癌查效率.
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