聚糖FUCOPOL在方向结中的冰调节效应
Bruno M Guerreiro1,2, Leo T Lou3, Boris Rubinsky3
1UCIBIO - Applied Molecular Biosciences Unit, Department of Chemistry, School of Science and Technology, NOVA University Lisbon, Caparica, Portugal. a4406@fct.unl.pt.
Soft matter
|November 15, 2023
概括
生物基多糖化合物FucoPol在定向结过程中重塑冰晶,为冷生物学和组织工程创造了对齐的结构. 这种冰模块化增强了冷保护,并使冷印刷的新应用成为可能.
科学领域:
- 材料科学 材料科学 材料科学
- 生物技术是生物技术.
- 低温生物学 低温生物学
背景情况:
- 定向结利用冰晶的生长来创建冷生物学和冷印刷中的对齐结构.
- 富含富可糖的多糖化物FucoPol,此前已经证明了冷保护作用和改变冰晶尺寸.
- 了解FucoPol的冰调节特性是其在先进材料结构中的应用的关键.
研究的目的:
- 研究FucoPol在定向结过程中对冰晶形态的冰调节效应.
- 描述由FucoPol引起的结构变化,并将其与已知的冰形成机制进行比较.
- 探索FucoPol在冷印刷和组织工程中的潜在应用.
主要方法:
- 使用不同度的FucoPol.进行了方向结实验.
- 分析了冰晶形态的对齐,对称性和厚度.
- 进行了接触角测量和粘度评估.
主要成果:
- 富科波尔将异型冰树突转化为线性对齐的,薄的,同型的或管状.
- 观察到增强的对齐 (3倍),尖端对称 (5.9倍) 和减少厚度 (5.3倍).
- 富科波尔的冰调节效应取决于度,类似于抗蛋白活性.
结论:
- 富科波尔具有显著的冰调节能力,增强其冷保护性质.
- 富科波尔溶液的高粘度在冰结构形成中起着至关重要的作用.
- 对于需要控制冰的增长的应用,如冷生物打印和组织工程等,FucoPol显示出有前途,提供一种可生物降解和无毒的替代品.
更多相关视频
08:59A Freeze-Thawing Method to Prepare Chitosan-Polyvinyl alcohol Hydrogels Without Crosslinking Agents and Diflunisal Release Studies
Published on: January 14, 2020
17.6K
09:20Microhoneycomb Monoliths Prepared by the Unidirectional Freeze-drying of Cellulose Nanofiber Based Sols: Method and Extensions
Published on: May 24, 2018
8.9K
相关概念视频
03:12Freezing Point Depression and Boiling Point Elevation
34.9K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
34.9K
01:23Membrane Fluidity
152.7K
Cell membranes are composed of phospholipids, proteins, and carbohydrates loosely attached to one another through chemical interactions. Molecules are generally able to move about in the plane of the membrane, giving the membrane its flexible nature called fluidity. Two other features of the membrane contribute to membrane fluidity: the chemical structure of the phospholipids and the presence of cholesterol in the membrane.
152.7K
02:45Responses to Heat and Cold Stress
13.5K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
13.5K