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Updated: Jul 11, 2025

Measurement of Protein Turnover Rates in Senescent and Non-Dividing Cultured Cells with Metabolic Labeling and Mass Spectrometry
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分支链氨基酸积累为衰老相关的分泌表现型提供燃料

Yaosi Liang1, Christopher Pan1, Tao Yin1

  • 1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27710, USA.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|November 15, 2023
PubMed
概括

改变的分支链氨基酸 (BCAA) 代谢通过激活mTORC1.1.驱动细胞衰老和炎症. 调节BCAA水平可能为与年龄有关的疾病提供新的治疗方法.

关键词:
BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA BCAA在 SASP 找 SASP与年龄有关的炎症.在 mTORC1 的情况下,mTORC1 是衰老是一种老化.

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