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Updated: Jul 11, 2025

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
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Published on: April 17, 2013

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在晚期甲状腺癌中,CDK4酸化状态和合理使用用于结合CDK4/6和BRAF/MEK抑制

Jaime M Pita1, Eric Raspé1, Katia Coulonval1

  • 1Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM) and Université Libre de Bruxelles (ULB)-Cancer Research Center (U-CRC), Université Libre de Bruxelles (ULB), Brussels, Belgium.

Frontiers in endocrinology
|November 15, 2023
PubMed
概括

循环素依赖性激酶4/6抑制剂 (CDK4/6i) 在治疗晚期甲状腺癌方面表现有前途,特别是在与BRAF/MEK抑制剂结合使用时. 检测CDK4酸化可以确定那些对CDK4/6i治疗有反应的患者.

关键词:
在ATC中,ATC是ATC.CDK4 Thr172 - 酸化的方法在PDTC中使用PDTC.生物标志物 生物标志物达布拉芬尼布的使用情况这是palbocicliblib.特拉美丁尼布 (trametinib) 是一种药物.

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