在COVID-19大流行期间,在二级护理环境中处方抗菌药物
Michael M Tadros1,2, Marian S Boshra3, Michael Scott4
1School of Pharmacy and Pharmaceutical Sciences, Ulster University, Coleraine, UK.
在COVID-19大流行之前和期间,抗菌素处方模式保持稳定. 抗菌药物管理计划是保持对医院抗菌药物使用的控制的关键.
科学领域:
- 传染性疾病 传染性疾病
- 医院 医院药房 医院药房
- 公共卫生 公共卫生
背景情况:
- 抗菌素耐药性 (AMR) 的上升限制了治疗选择,增加了医疗保健成本.
- 有效的抗微生物药物管理对于患者的治疗结果和医院资源管理至关重要.
研究的目的:
- 分析和比较北爱尔兰两个地区医院的抗菌素处方做法.
- 评估COVID-19大流行对抗微生物药物利用和遵守指南的影响.
主要方法:
- 采用了一种混合前性-后性研究设计.
- 使用全球点流行调查 (GPPS) 收集数据.
- 在大流行前 (2019年) 和大流行 (2021年) 期间,对处方模式进行了比较.
主要成果:
- 591名患者中的43.8%接受了402种抗微生物药物,其中82.8%接受实证治疗.
- 没有观察到患者数量或抗菌素使用的显著变化.
- 在大流行期间,指导方针的遵守略有下降3.3% (66.2%) 与2019年 (69.5%) 相比.
- 生物标志物导向治疗从83.5% (2019年) 降至81.5% (2021年).
结论:
- 在研究的医院中,COVID-19大流行并没有显著改变抗菌素处方模式.
- 在疫情期间,抗微生物药物管理计划在管理抗微生物药物消费方面表现出有效性.
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