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Updated: Jul 11, 2025

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在遗传性 papillary 细胞癌中发现的具有激活 N- 叶子突变的 MET 变异仍然需要连接体刺激

Célia Guérin, Audrey Vinchent, Marie Fernandes

    bioRxiv : the preprint server for biology
    |November 15, 2023
    PubMed
    概括

    在遗传性乳头性细胞癌中,新的MET突变需要肝细胞生长因子 (HGF) 来激活,而不是其他受体氨酸激酶 (RTK) 变体. 这一发现表明,针对高基因基因依赖MET突变的向疗法.

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